部(bu)分化(hua)妝品(pin)原料檢測方法(fa)有(you)哪些1、酸(suan)值(zhi)測定(ding)(ding)的(de)(de)(de)(de)方法(fa)是對(dui)于溶(rong)解(jie)(jie)于醇(chun)(chun)—醚中(zhong)(zhong)(zhong)的(de)(de)(de)(de)規(gui)定(ding)(ding)試(shi)(shi)(shi)樣(yang)液(ye)(ye)(ye)(ye)和(he)對(dui)照空(kong)白液(ye)(ye)(ye)(ye)，用(yong)標(biao)定(ding)(ding)過的(de)(de)(de)(de)氫(qing)(qing)(qing)氧(yang)化(hua)鉀液(ye)(ye)(ye)(ye)進行滴定(ding)(ding)至(zhi)酚酞(tai)終(zhong)點(dian)。(1)試(shi)(shi)(shi)樣(yang)制備按待測試(shi)(shi)(shi)樣(yang)酸(suan)值(zhi)的(de)(de)(de)(de)大(da)小(估(gu)計(ji))，若酸(suan)值(zhi)1.0mg，規(gui)定(ding)(ding)取(qu)樣(yang)量2g。將規(gui)定(ding)(ding)試(shi)(shi)(shi)樣(yang)量放人(ren)125ml錐形燒瓶中(zhong)(zhong)(zhong)，加(jia)入(ru)(ru)25ml中(zhong)(zhong)(zhong)性乙(yi)醇(chun)(chun)，混(hun)合使之溶(rong)解(jie)(jie)，如需(xu)要(yao)，可(ke)在(zai)(zai)水(shui)浴(yu)上加(jia)熱，冷(leng)卻(que)。另再(zai)加(jia)入(ru)(ru)25ml無(wu)水(shui)**并(bing)混(hun)合，如需(xu)要(yao)可(ke)加(jia)熱，方法(fa)如前。即制備好試(shi)(shi)(shi)樣(yang)液(ye)(ye)(ye)(ye)。另配制一個空(kong)白試(shi)(shi)(shi)液(ye)(ye)(ye)(ye)，不(bu)加(jia)入(ru)(ru)試(shi)(shi)(shi)樣(yang)，只有(you)25ml無(wu)水(shui)**和(he)25ml無(wu)水(shui)中(zhong)(zhong)(zhong)性乙(yi)醇(chun)(chun)。(2)滴定(ding)(ding)試(shi)(shi)(shi)液(ye)(ye)(ye)(ye)分別加(jia)入(ru)(ru)lml酚酞(tai)溶(rong)液(ye)(ye)(ye)(ye)于試(shi)(shi)(shi)樣(yang)液(ye)(ye)(ye)(ye)和(he)空(kong)白試(shi)(shi)(shi)液(ye)(ye)(ye)(ye)中(zhong)(zhong)(zhong)，再(zai)用(yong)0.1mol/L氫(qing)(qing)(qing)氧(yang)化(hua)鉀溶(rong)液(ye)(ye)(ye)(ye)分別滴定(ding)(ding)，邊(bian)滴定(ding)(ding)邊(bian)頻(pin)(pin)頻(pin)(pin)搖動，直(zhi)到(dao)溶(rong)液(ye)(ye)(ye)(ye)呈粉紅色并(bing)保持30s而終(zhong)止。正確讀出滴定(ding)(ding)用(yong)氫(qing)(qing)(qing)氧(yang)化(hua)鉀標(biao)準(zhun)溶(rong)液(ye)(ye)(ye)(ye)的(de)(de)(de)(de)體積(ji)(m1)(準(zhun)確到(dao)小數后(hou)二位)。2、皂化(hua)值(zhi)測定(ding)(ding)的(de)(de)(de)(de)方法(fa)是稱(cheng)取(qu)一定(ding)(ding)的(de)(de)(de)(de)試(shi)(shi)(shi)樣(yang)，溶(rong)解(jie)(jie)在(zai)(zai)乙(yi)醇(chun)(chun)中(zhong)(zhong)(zhong)，和(he)定(ding)(ding)量加(jia)入(ru)(ru)氫(qing)(qing)(qing)氧(yang)化(hua)鉀的(de)(de)(de)(de)甲(jia)醇(chun)(chun)溶(rong)液(ye)(ye)(ye)(ye)回流。試(shi)(shi)(shi)樣(yang)中(zhong)(zhong)(zhong)存在(zai)(zai)的(de)(de)(de)(de)酯在(zai)(zai)此(ci)情況(kuang)下會(hui)反(fan)應成(cheng)為(wei)(wei)鉀皂，任何存在(zai)(zai)的(de)(de)(de)(de)游(you)離酸(suan)也會(hui)形成(cheng)鉀皂。同時(shi)作空(kong)白試(shi)(shi)(shi)驗。在(zai)(zai)回流以后(hou)，用(yong)標(biao)定(ding)(ding)過的(de)(de)(de)(de)硫酸(suan)滴定(ding)(ding)空(kong)白和(he)試(shi)(shi)(shi)樣(yang)到(dao)酚酞(tai)終(zhong)點(dian)。中(zhong)(zhong)(zhong)和(he)空(kong)白和(he)試(shi)(shi)(shi)樣(yang)所用(yong)酸(suan)量的(de)(de)(de)(de)差(cha)即為(wei)(wei)試(shi)(shi)(shi)樣(yang)所消耗的(de)(de)(de)(de)氫(qing)(qing)(qing)氧(yang)化(hua)鉀量。每克試(shi)(shi)(shi)樣(yang)所需(xu)的(de)(de)(de)(de)氫(qing)(qing)(qing)氧(yang)化(hua)鉀毫克數即為(wei)(wei)皂化(hua)值(zhi)。(1)試(shi)(shi)(shi)樣(yang)制備按待測試(shi)(shi)(shi)樣(yang)酸(suan)值(zhi)的(de)(de)(de)(de)大(da)小(估(gu)計(ji))，若皂化(hua)值(zhi)化(hua)妝品(pin)芳香功效評價，選(xuan)微譜！洗面奶化(hua)妝品(pin)功效評價化(hua)妝品(pin)功效檢驗機(ji)構

年來，隨著(zhu)生命科學和(he)生物工(gong)程技(ji)術研究的(de)(de)(de)(de)快速發展(zhan)，對(dui)化(hua)妝(zhuang)(zhuang)品(pin)(pin)(pin)的(de)(de)(de)(de)研制(zhi)已逐漸從主要重(zhong)視安(an)(an)全(quan)性(xing)轉變為安(an)(an)全(quan)性(xing)和(he)功(gong)(gong)效(xiao)性(xing)并(bing)重(zhong)的(de)(de)(de)(de)時代。為加強對(dui)化(hua)妝(zhuang)(zhuang)品(pin)(pin)(pin)安(an)(an)全(quan)性(xing)和(he)功(gong)(gong)效(xiao)性(xing)的(de)(de)(de)(de)管(guan)理(li)，國家(jia)食(shi)品(pin)(pin)(pin)藥品(pin)(pin)(pin)監(jian)督管(guan)理(li)局要求化(hua)妝(zhuang)(zhuang)品(pin)(pin)(pin)生產(chan)(chan)(chan)企業在產(chan)(chan)(chan)品(pin)(pin)(pin)上市前(qian)需對(dui)化(hua)妝(zhuang)(zhuang)品(pin)(pin)(pin)功(gong)(gong)效(xiao)宣稱及安(an)(an)全(quan)性(xing)進行評(ping)(ping)(ping)價(jia)，評(ping)(ping)(ping)價(jia)合格的(de)(de)(de)(de)產(chan)(chan)(chan)品(pin)(pin)(pin)方可(ke)上市銷售。消毒劑、化(hua)妝(zhuang)(zhuang)品(pin)(pin)(pin)等化(hua)學化(hua)工(gong)產(chan)(chan)(chan)品(pin)(pin)(pin)在原料生產(chan)(chan)(chan)、成品(pin)(pin)(pin)生產(chan)(chan)(chan)過程中，會因化(hua)學反應、生產(chan)(chan)(chan)工(gong)藝等原因混入(ru)一些有(you)毒副產(chan)(chan)(chan)物，對(dui)人體造成傷害。為保障(zhang)消毒產(chan)(chan)(chan)品(pin)(pin)(pin)、化(hua)妝(zhuang)(zhuang)品(pin)(pin)(pin)等化(hua)學化(hua)工(gong)產(chan)(chan)(chan)品(pin)(pin)(pin)在日常使用過程中的(de)(de)(de)(de)安(an)(an)全(quan)性(xing)，國家(jia)相(xiang)關部門要求此類產(chan)(chan)(chan)品(pin)(pin)(pin)上市前(qian)必須考核(he)其毒理(li)學指標，毒理(li)考察合格的(de)(de)(de)(de)產(chan)(chan)(chan)品(pin)(pin)(pin)方可(ke)上市銷售。洗面奶化(hua)妝(zhuang)(zhuang)品(pin)(pin)(pin)功(gong)(gong)效(xiao)評(ping)(ping)(ping)價(jia)化(hua)妝(zhuang)(zhuang)品(pin)(pin)(pin)功(gong)(gong)效(xiao)檢驗機構化(hua)妝(zhuang)(zhuang)品(pin)(pin)(pin)卸妝(zhuang)(zhuang)功(gong)(gong)效(xiao)評(ping)(ping)(ping)價(jia)，選微譜！

申請日化產(chan)品(pin)新原料(liao)注冊或(huo)備案中(zhong)的(de)研(yan)(yan)制報告包(bao)(bao)(bao)括哪些內(nei)容1.研(yan)(yan)發背景，包(bao)(bao)(bao)括原料(liao)研(yan)(yan)發的(de)目(mu)的(de)、意義(yi)、管理分(fen)類、相關的(de)技(ji)術資料(liao)包(bao)(bao)(bao)括知(zhi)識產(chan)權方面和(he)原料(liao)在國(guo)內(nei)外的(de)新研(yan)(yan)究進展等內(nei)容。2.基本(ben)信息，包(bao)(bao)(bao)括名稱、來源、相對分(fen)子質量(liang)、分(fen)子式、化學(xue)結(jie)構等。3.使(shi)(shi)(shi)用(yong)(yong)目(mu)的(de)等關鍵(jian)信息，應說(shuo)明(ming)原料(liao)在化妝品(pin)中(zhong)的(de)使(shi)(shi)(shi)用(yong)(yong)目(mu)的(de)、適應或(huo)使(shi)(shi)(shi)用(yong)(yong)范圍、使(shi)(shi)(shi)用(yong)(yong)規格、基于安全的(de)使(shi)(shi)(shi)用(yong)(yong)限量(liang)和(he)依據、注意事項、警示語等。4.國(guo)外（地(di)(di)區）使(shi)(shi)(shi)用(yong)(yong)情況，應說(shuo)明(ming)原料(liao)在國(guo)外（地(di)(di)區）是否使(shi)(shi)(shi)用(yong)(yong)于化妝品(pin)的(de)情況。包(bao)(bao)(bao)括在售國(guo)家。

化(hua)(hua)妝品鉛(qian)汞(gong)檢測方法1、取出少許(xu)化(hua)(hua)妝品，涂抹在(zai)一(yi)(yi)張(zhang)白(bai)紙上(shang)，或(huo)者薄塑料膜上(shang)，放在(zai)陽光下(或(huo)者自然(ran)環境(jing))，如果(guo)(guo)變(bian)(bian)黑，說(shuo)(shuo)明(ming)(ming)護膚(fu)(fu)(fu)品里可(ke)能含(han)鉛(qian)超標。2、將(jiang)少許(xu)化(hua)(hua)妝品涂抹在(zai)白(bai)紙上(shang)，等(deng)(deng)上(shang)一(yi)(yi)會兒，等(deng)(deng)它在(zai)紙上(shang)滲透后，用硬幣的(de)(de)立面來回的(de)(de)劃，如果(guo)(guo)沒有任何變(bian)(bian)化(hua)(hua)，就可(ke)以(yi)初步說(shuo)(shuo)明(ming)(ming)不含(han)鉛(qian)，如果(guo)(guo)變(bian)(bian)黑了(le)說(shuo)(shuo)明(ming)(ming)含(han)鉛(qian)，顏色越深，含(han)鉛(qian)量越高。3、取一(yi)(yi)些化(hua)(hua)妝品滴在(zai)清水中，如果(guo)(guo)它沉在(zai)水底說(shuo)(shuo)明(ming)(ming)其中含(han)有鉛(qian)汞(gong)等(deng)(deng)重金(jin)屬物質，如果(guo)(guo)浮(fu)在(zai)水面說(shuo)(shuo)明(ming)(ming)含(han)動物油不益皮(pi)(pi)膚(fu)(fu)(fu)呼吸透氣，能夠融(rong)解在(zai)水中是好(hao)的(de)(de)。擴展資料：其實美白(bai)淡斑類(lei)化(hua)(hua)妝品汞(gong)超標的(de)(de)問(wen)題由來已久(jiu)，汞(gong)除了(le)可(ke)以(yi)通(tong)過吸入(ru)或(huo)食入(ru)，還可(ke)通(tong)過皮(pi)(pi)膚(fu)(fu)(fu)的(de)(de)表皮(pi)(pi)、汗腺、皮(pi)(pi)脂腺和等(deng)(deng)皮(pi)(pi)膚(fu)(fu)(fu)附件進入(ru)體(ti)內，除了(le)會對(dui)人體(ti)的(de)(de)腎臟造(zao)成傷害導致腎病綜合征等(deng)(deng)外，還可(ke)對(dui)神經系統造(zao)成不同程度(du)的(de)(de)傷害。化(hua)(hua)妝品爽身功效評價，找微譜！

特(te)(te)殊(shu)化妝(zhuang)(zhuang)品(pin)(pin)(pin)備(bei)案生(sheng)(sheng)產衛生(sheng)(sheng)條件審(shen)(shen)(shen)(shen)(shen)(shen)核(he)(he)(he)(he)： 1、準備(bei)衛生(sheng)(sheng)條件審(shen)(shen)(shen)(shen)(shen)(shen)核(he)(he)(he)(he)資料(liao)(liao)，包括申(shen)請(qing)表，配方(fang)表，生(sheng)(sheng)產工藝簡(jian)述和簡(jian)圖(tu)，生(sheng)(sheng)產許可(ke)(ke)證，抽樣(yang)(yang)申(shen)請(qing)表。（此(ci)處的(de)(de)(de)(de)配方(fang)表必須是在(zai)申(shen)報(bao)系統中填報(bao)的(de)(de)(de)(de)，帶條碼的(de)(de)(de)(de)打印配方(fang)表） 2、衛生(sheng)(sheng)條件審(shen)(shen)(shen)(shen)(shen)(shen)核(he)(he)(he)(he)資料(liao)(liao)企業(ye)蓋(gai)章簽字后，送當地(di)省局申(shen)請(qing)審(shen)(shen)(shen)(shen)(shen)(shen)核(he)(he)(he)(he)。（可(ke)(ke)能(neng)會產生(sheng)(sheng)審(shen)(shen)(shen)(shen)(shen)(shen)評(ping)的(de)(de)(de)(de)費用，需遵循當地(di)省局規(gui)定繳納） 3、省局審(shen)(shen)(shen)(shen)(shen)(shen)核(he)(he)(he)(he)完(wan)成后，取回省局已經(jing)確認的(de)(de)(de)(de)衛生(sheng)(sheng)條件審(shen)(shen)(shen)(shen)(shen)(shen)核(he)(he)(he)(he)資料(liao)(liao)，并等待樣(yang)(yang)品(pin)(pin)(pin)封(feng)樣(yang)(yang)。 4、封(feng)樣(yang)(yang)完(wan)成后，就可(ke)(ke)進入檢測階(jie)段(duan)。特(te)(te)殊(shu)化妝(zhuang)(zhuang)品(pin)(pin)(pin)備(bei)案報(bao)批過程(cheng) 1、整理并完(wan)善申(shen)報(bao)資料(liao)(liao)，遞交受理中心 2、資料(liao)(liao)通過形(xing)式審(shen)(shen)(shen)(shen)(shen)(shen)核(he)(he)(he)(he)，受理中心出(chu)具(ju)受理通知書（需時(shi)5個工作日(ri)(ri)） 3、化妝(zhuang)(zhuang)品(pin)(pin)(pin)評(ping)審(shen)(shen)(shen)(shen)(shen)(shen)中心審(shen)(shen)(shen)(shen)(shen)(shen)評(ping)（需時(shi)40個工作日(ri)(ri)） 4、制證、發證（需時(shi)10個工作日(ri)(ri)）人的(de)(de)(de)(de)皮膚(fu)各有不(bu)(bu)同，所以每一種護膚(fu)品(pin)(pin)(pin)的(de)(de)(de)(de)制造成分(fen)不(bu)(bu)一樣(yang)(yang)，根據不(bu)(bu)同皮膚(fu)的(de)(de)(de)(de)性質也就不(bu)(bu)一樣(yang)(yang)。洗面(mian)奶化妝(zhuang)(zhuang)品(pin)(pin)(pin)功效評(ping)價(jia)化妝(zhuang)(zhuang)品(pin)(pin)(pin)功效檢驗機構

化(hua)妝品美白功(gong)效評(ping)價，找微譜！洗面奶化(hua)妝品功(gong)效評(ping)價化(hua)妝品功(gong)效檢驗機構

需要功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)性(xing)測試(shi)的(de)(de)(de)(de)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)1.具有抗皺、緊致、舒緩、控(kong)油、去角質、防斷(duan)發(fa)(fa)和(he)(he)去屑功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)，以及宣(xuan)稱溫和(he)(he)（如(ru)無刺(ci)激(ji)）或量化(hua)(hua)(hua)指標（如(ru)功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)宣(xuan)稱保(bao)持(chi)時間、功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)宣(xuan)稱相(xiang)關(guan)統計數據等(deng)）的(de)(de)(de)(de)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)，應當通過(guo)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)評(ping)(ping)(ping)(ping)(ping)價(jia)試(shi)驗(yan)和(he)(he)研究(jiu)數據分(fen)(fen)析(xi)(xi)(xi)的(de)(de)(de)(de)結果，進(jin)行功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)宣(xuan)稱評(ping)(ping)(ping)(ping)(ping)價(jia)。2.具有淡斑美白、防曬、防脫(tuo)發(fa)(fa)、改善痘痘、滋養和(he)(he)修護功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)的(de)(de)(de)(de)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)，應當由(you)(you)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)注冊(ce)和(he)(he)備(bei)案(an)檢(jian)驗(yan)機構按照強制性(xing)國家標準、技術規范的(de)(de)(de)(de)要求(qiu)開展人體(ti)功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)評(ping)(ping)(ping)(ping)(ping)價(jia)試(shi)驗(yan)，并(bing)出(chu)具報告(gao)。3.進(jin)行特定宣(xuan)稱的(de)(de)(de)(de)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)（如(ru)宣(xuan)稱適用敏(min)感皮膚、宣(xuan)稱無淚配方(fang)(fang)(fang)），應當通過(guo)人體(ti)功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)評(ping)(ping)(ping)(ping)(ping)價(jia)試(shi)驗(yan)或消費者使用測試(shi)的(de)(de)(de)(de)方(fang)(fang)(fang)式(shi)進(jin)行功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)宣(xuan)稱評(ping)(ping)(ping)(ping)(ping)價(jia)。主要的(de)(de)(de)(de)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)測試(shi)方(fang)(fang)(fang)法(fa)1.理化(hua)(hua)(hua)分(fen)(fen)析(xi)(xi)(xi)法(fa)采(cai)用稱重法(fa)評(ping)(ping)(ping)(ping)(ping)判化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)的(de)(de)(de)(de)吸濕(shi)性(xing)和(he)(he)保(bao)濕(shi)性(xing)，或對(dui)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)中的(de)(de)(de)(de)保(bao)濕(shi)活性(xing)成分(fen)(fen)進(jin)行定量分(fen)(fen)析(xi)(xi)(xi)。2.細胞生物(wu)(wu)法(fa)則(ze)通過(guo)研究(jiu)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)對(dui)細胞中保(bao)濕(shi)相(xiang)關(guan)基(ji)(ji)因（如(ru)絲聚蛋(dan)白、透明質酸合成酶(mei)）表(biao)達情況的(de)(de)(de)(de)影(ying)響進(jin)行評(ping)(ping)(ping)(ping)(ping)價(jia)。3.生物(wu)(wu)化(hua)(hua)(hua)學法(fa)包括消除自由(you)(you)基(ji)(ji)實(shi)驗(yan)、超氧陰(yin)離子自由(you)(you)基(ji)(ji)實(shi)驗(yan)、羥自由(you)(you)基(ji)(ji)實(shi)驗(yan)、氧自由(you)(you)基(ji)(ji)吸附能(neng)力實(shi)驗(yan)、抑制金屬蛋(dan)白酶(mei)和(he)(he)彈性(xing)蛋(dan)白酶(mei)實(shi)驗(yan)。洗面奶化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)評(ping)(ping)(ping)(ping)(ping)價(jia)化(hua)(hua)(hua)妝(zhuang)(zhuang)(zhuang)品(pin)(pin)(pin)(pin)功(gong)(gong)(gong)效(xiao)(xiao)(xiao)(xiao)(xiao)(xiao)檢(jian)驗(yan)機構

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